Rhubarb enhances gastrointestinal motility via calcium-mediated intestinal acetylcholine release: a network pharmacology study

Abstract Rapid restoration of intestinal motility is crucial in managing acute pancreatitis (AP), particularly in severe cases. This study aims to investigate the potential of Chinese medicinal rhubarb to enhance bowel motility through modulation of calcium ion signaling in the gastrointestinal trac...

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Hlavní autoři:	Zhiyong Wen, Weihua Liu, Jialing Li, Songling Tan, Jianbo Wen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Scientific Reports
Témata:	Acute pancreatitis Rhubarb Calcium ion pathway Network pharmacology
On-line přístup:	https://doi.org/10.1038/s41598-026-39372-z
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