A humanized NOG‐EXL mouse model for producing severe fever with thrombocytopenia syndrome virus–reactive human antibodies

Abstract Background Humanized mouse models are essential for studying the human immune response and antibody development. However, conventional models show limited B cell maturation and antigen‐specific humoral responses. To overcome these limitations, we used the NOG‐EXL mice expressing human inter...

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Huvudupphov:	Dong Hoon Lee, Jiyeong Bae, Sumi Kim, Chan Young Song, Jung Hyu Shin, Eun Hee Kim, Chan Ho Jang, Young‐sun Yun, Dong‐sook Lee, Hyuk Chu, Jang‐Hoon Choi, Chan Woo Kim
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2026-02-01
Serie:	Animal Models and Experimental Medicine
Ämnen:	human immunoglobulin G (IgG) humanized mouse severe fever with thrombocytopenia syndrome virus (SFTSV)
Länkar:	https://doi.org/10.1002/ame2.70140
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