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Repeated cold exposures protect a mouse model of Alzheimer's disease against cold-induced tau phosphorylation

Objective: Old age is associated with a rise in the incidence of Alzheimer's disease (AD) but also with thermoregulatory deficits. Indicative of a link between the two, hypothermia induces tau hyperphosphorylation. The 3xTg-AD mouse model not only develops tau and amyloid pathologies in the brain bu...

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Xehetasun bibliografikoak
Egile Nagusiak: Marine Tournissac, Philippe Bourassa, Ruben D. Martinez-Cano, Tra-My Vu, Sébastien S. Hébert, Emmanuel Planel, Frédéric Calon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019-04-01
Saila:Molecular Metabolism
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2212877818309918
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