Microenvironment-driven satellite cell regeneration and repair in aging-related sarcopenia: mechanisms and therapeutic frontiers

Abstract Sarcopenia, a progressive age-related decline in skeletal muscle mass and function, is closely linked to impaired regenerative capacity of satellite cells (SCs), also known as satellite cells. Age-dependent SCs dysfunction, driven by intrinsic senescence and niche dysregulation, disrupts ac...

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Detalhes bibliográficos

Principais autores:	Na Li, Yushu Chen, Qiong Wang, Xiaoqin Liu, Chao Han, Chao Qu, Xin Guan, Wei Zou, Xiaomin Wang, Ang Li, Jing Liu, Yanfu Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-10-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Muscle stem cells (MuSCs) Satellite cells (SCs) Satellite cell niche Fibro adipogenic precursors (FAPs) Extracellular matrix (ECM)
Acesso em linha:	https://doi.org/10.1186/s13287-025-04481-5
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