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Facile synthesis of PEI-based crystalline templated mesoporous silica with molecular chirality for improved oral delivery of the poorly water-soluble drug

The aim of this study was to build up a novel chiral mesoporous silica called PEIs@TA-CMS through a facile biomimetic strategy and to explore its potential to serve as a drug carrier for improving the delivery efficiency of poorly water-soluble drug. PEIs@TA-CMS was synthesized by using a chiral cry...

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Principais autores: Wei Xin, Yumei Wang, Yan Bian, Jiahui Lin, Wenhao Weng, Xinyi Zhao, Kaijun Gou, Xianmou Guo, Heran Li
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis Group 2021-01-01
סדרה:Drug Delivery
נושאים:
biomimetic synthesis
chiral mesoporous silica
drug delivery
oral bioavailability
nimodipine
גישה מקוונת:http://dx.doi.org/10.1080/10717544.2021.1912212
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