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Auditory mismatch responses are differentially sensitive to changes in muscarinic acetylcholine versus dopamine receptor function

The auditory mismatch negativity (MMN) has been proposed as a biomarker of NMDA receptor (NMDAR) dysfunction in schizophrenia. Such dysfunction may be caused by aberrant interactions of different neuromodulators with NMDARs, which could explain clinical heterogeneity among patients. In two studies (...

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Principais autores: Lilian Aline Weber, Sara Tomiello, Dario Schöbi, Katharina V Wellstein, Daniel Mueller, Sandra Iglesias, Klaas Enno Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2022-05-01
coleção:eLife
Assuntos:
mismatch negativity
acetylcholine
dopamine
NMDA receptor
schizophrenia
volatility
Acesso em linha:https://elifesciences.org/articles/74835
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