Shared genetic architecture between depression and migraine: a large-scale genome-wide cross-trait analysis

Abstract Background Depression and migraine are highly prevalent neuropsychiatric disorders that frequently co-occur. However, the extent to which they share genetic determinants, particularly for postpartum depression (PPD), an underexplored subtype, remains insufficiently understood. Methods We pe...

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Hlavní autoři:	Min Zhang, Qiyin Li, Yuan Zhao, Yadong Peng, Jiangyou Yu, Cheng Gan, Liwei Tang, Keyi Liu, Ying Liu, Zheng Zhang, Xinglian Wang, Mingshuang Tang, Chenggang Jiang, Dongqing Gu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-05-01
Edice:	The Journal of Headache and Pain
Témata:	Cross-trait analysis Depression Mendelian randomization Migraine Postpartum depression Pleiotropic loci
On-line přístup:	https://doi.org/10.1186/s10194-026-02402-2
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