ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism

Angiopoietin-like protein 3 (ANGPTL3) is a hepatically secreted protein and therapeutic target for reducing plasma triglyceride-rich lipoproteins and low-density lipoprotein (LDL) cholesterol. Although ANGPTL3 modulates the metabolism of circulating lipoproteins, its role in triglyceride-rich lipopr...

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Bibliografski detalji

Glavni autori:	Kendall H. Burks, Yan Xie, Michael Gildea, In-Hyuk Jung, Sandip Mukherjee, Paul Lee, Upasana Pudupakkam, Ryan Wagoner, Ved Patel, Katherine Santana, Arturo Alisio, Ira J. Goldberg, Brian N. Finck, Edward A. Fisher, Nicholas O. Davidson, Nathan O. Stitziel
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-02-01
Serija:	Journal of Lipid Research
Teme:	apolipoproteins dyslipidemias LDL/metabolism lipase/endothelial PPARs triglycerides
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0022227524000051
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