Omission of dexamethasone in paclitaxel premedication regimens: protocol of the multicentre, randomised, non-inferiority DEXASTOP trial

Introduction Standard premedication for paclitaxel-based chemotherapy includes dexamethasone and an histamine 1-antagonist to prevent hypersensitivity reactions (HSRs). However, the pharmacological rationale for dexamethasone is limited, and its use is associated with adverse effects such as hypergl...

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Principais autores:	Birgit C P Koch, Virgil A S H Dalm, Leontine E A M M Spierings, Michiel Zietse, Luuk C Aalders, Nikki De Rouw, Wouter Dercksen, Frederick W Thielen, Leni van Doorn, Roelof W F van Leeuwen
格式:	Artigo
語言:	Inglês
出版:	BMJ Publishing Group 2025-04-01
叢編:	BMJ Open
在線閱讀:	https://bmjopen.bmj.com/content/15/4/e102770.full
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