Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some <i>N</i>-Substituted-4-Phenothiazine-Chalcones

Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are two attractive targets in the discovery of novel substances that could control multiple aspects of Alzheimer’s disease (AD). Chalcones are the flavonoid derivatives with diverse bioactivities, including AChE and BACE-1 inhibition. In this s...

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Autors principals:	Thai-Son Tran, Minh-Tri Le, Thi-Cam-Vi Nguyen, The-Huan Tran, Thanh-Dao Tran, Khac-Minh Thai
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-08-01
Col·lecció:	Molecules
Matèries:	in silico QSAR docking chalcone acetylcholiesterase inhibitor BACE-1
Accés en línia:	https://www.mdpi.com/1420-3049/25/17/3916
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