New insights on mitochondrial heteroplasmy observed in ovarian diseases

Background: The reportedly high mutation rate of mitochondrial DNA (mtDNA) may be attributed to the absence of histone protection and complete repair mechanisms. Mitochondrial heteroplasmy refers to the coexistence of wild-type and mutant mtDNA. Most healthy individuals carry a low point mutation lo...

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Principais autores:	Yong Zhou, Yang Jin, Tianyu Wu, Yinfeng Wang, Yuanhang Dong, Pei Chen, Changchang Hu, Ningping Pan, Chaoshuang Ye, Li Shen, Mengyan Lin, Tao Fang, Ruijin Wu
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-11-01
叢編:	Journal of Advanced Research
主題:	Mitochondrial heteroplasmy Polycystic ovary syndrome Premature ovarian insufficiency Endometriosis Mitochondria-targeted therapy
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2090123223003727
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