A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis

Summary: Background: MicroRNAs are non-coding RNAs that negatively regulate gene networks. Previously, we reported that systemically delivered miR-29 mimic MRG-201 reduced fibrosis in animal models, supporting the consideration of miR-29-based therapies for idiopathic pulmonary fibrosis (IPF). Meth...

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Bibliografiske detaljer

Principais autores:	Maurizio Chioccioli, Subhadeep Roy, Rachel Newell, Linda Pestano, Brent Dickinson, Kevin Rigby, Jose Herazo-Maya, Gisli Jenkins, Steward Ian, Gauri Saini, Simon R. Johnson, Rebecca Braybrooke, Guying Yu, Maor Sauler, Farida Ahangari, Shuizi Ding, Joseph DeIuliis, Nachelle Aurelien, Rusty L. Montgomery, Naftali Kaminski
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2022-11-01
Serier:	EBioMedicine
Fag:	Idiopathic pulmonary fibrosis MicroRNA miR-29 RNA therapies
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2352396422004868
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