The p75NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability

Abstract The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase the expression of the p75NTR pan-neurotrophin receptor. Even though p75NTR targeti...

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Detalhes bibliográficos

Principais autores:	Viviana Pérez, Francisca Bermedo-Garcia, Diego Zelada, Felipe A. Court, Miguel Ángel Pérez, Marco Fuenzalida, Johanna Ábrigo, Claudio Cabello-Verrugio, Guillermo Moya-Alvarado, Juan Carlos Tapia, Vicente Valenzuela, Claudio Hetz, Francisca C. Bronfman, Juan Pablo Henríquez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-09-01
coleção:	Acta Neuropathologica Communications
Assuntos:	Neuromuscular junction p75NTR Neurotrophin Motor neuron Synaptic vesicles
Acesso em linha:	http://link.springer.com/article/10.1186/s40478-019-0802-7
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