Novel Pyrazole-3-Cyano-2-Pyridinone Hybrids as Multitarget Anti-Inflammatory Agents: Synthesis, Computational Modeling, and Biological Evaluation

Bahgat RM Hussein,1 Ibrahim M Salem,2 Hossameldin A Aziz,3,4 Omar Alshazly,5,6 Heba A Hofny,5,6 Aliaa M Mohassab,7,8 Zuhier A Awan,9 Tarek S Ibrahim,10 Elsayed M Mahmoud,11,12 Stefan Bräse,13 Mamdouh FA Mohamed3– 5 1Department of Chemistry, Faculty of Science, Sohag University, Sohag, 82524, Egypt;...

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Autors principals:	Hussein BRM, Salem IM, Aziz HA, Alshazly O, Hofny HA, Mohassab AM, Awan ZA, Ibrahim TS, Mahmoud EM, Bräse S, Mohamed MFA
Format:	Artigo
Idioma:	Inglês
Publicat:	Dove Medical Press 2026-04-01
Col·lecció:	Drug Design, Development and Therapy
Matèries:	Pyrazole 3-Cyano-2-pyridinone Anti-inflammatory Healthcare COX2 iNOS
Accés en línia:	https://www.dovepress.com/novel-pyrazole-3-cyano-2-pyridinone-hybrids-as-multitarget-anti-inflam-peer-reviewed-fulltext-article-DDDT
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