Advanced Glycation End Products Impair Glucose-Stimulated Insulin Secretion of a Pancreatic β-Cell Line INS-1-3 by Disturbance of Microtubule Cytoskeleton via p38/MAPK Activation

Advanced glycation end products (AGEs) are believed to be involved in diverse complications of diabetes mellitus. Overexposure to AGEs of pancreatic β-cells leads to decreased insulin secretion and cell apoptosis. Here, to understand the cytotoxicity of AGEs to pancreatic β-cells, we used INS-1-3 ce...

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Bibliografische gegevens

Hoofdauteurs:	Jia You, Zai Wang, Shiqing Xu, Wenjian Zhang, Qing Fang, Honglin Liu, Liang Peng, Tingting Deng, Jinning Lou
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2016-01-01
Reeks:	Journal of Diabetes Research
Online toegang:	http://dx.doi.org/10.1155/2016/9073037
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