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Volumetric macromolecule identification in cryo-electron tomograms using capsule networks

Abstract Background Despite recent advances in cellular cryo-electron tomography (CET), developing automated tools for macromolecule identification in submolecular resolution remains challenging due to the lack of annotated data and high structural complexities. To date, the extent of the deep learn...

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Tallennettuna:
Päätekijät: Noushin Hajarolasvadi, Vikram Sunkara, Sagar Khavnekar, Florian Beck, Robert Brandt, Daniel Baum
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2022-08-01
Sarja:BMC Bioinformatics
Aiheet:
Biomedical imaging
Cellular cryo-electron tomography
Macromolecule identification
Deep learning
Capsule network
Linkit:https://doi.org/10.1186/s12859-022-04901-w
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