Hepatotoxicity prevention in Acetaminophen-induced HepG2 cells by red betel (Piper crocatum Ruiz and Pav) extract from Indonesia via antioxidant, anti-inflammatory, and anti-necrotic

Acetaminophen (APAP) is a widely used analgesic, but it may cause liver injury (hepatotoxicity) via oxidative stress that induced by N-acetyl-p-benzoquinone imine (NAPQI) in long term usage or overdose. Multiple inflammatory mediators were also found to contribute for this effect. Many medicinal pla...

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Autori principali:	Chrismis Novalinda Ginting, I Nyoman Ehrich Lister, Ermi Girsang, Wahyu Widowati, Dewani Tediana Yusepany, Alya Mardhotillah Azizah, Hanna Sari Widya Kusuma
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2021-01-01
Serie:	Heliyon
Soggetti:	Red betel leaves extract Acetaminophen HepG2 cells Hepatoprotective Biochemistry Immunology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405844020324634
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