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Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy.

Severe infection with respiratory syncytial virus (RSV) during infancy is strongly associated with the development of asthma. To identify genetic variation that contributes to asthma following severe RSV bronchiolitis during infancy, we sequenced the coding exons of 131 asthma candidate genes in 182...

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Principais autores: Dara G Torgerson, Tusar Giri, Todd E Druley, Jie Zheng, Scott Huntsman, Max A Seibold, Andrew L Young, Toni Schweiger, Huiqing Yin-Declue, Geneline D Sajol, Kenneth B Schechtman, Ryan D Hernandez, Adrienne G Randolph, Leonard B Bacharier, Mario Castro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4654486?pdf=render
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