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Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

This paper proposes the design of combination opioid–adrenergic tethered compounds to enhance efficacy and specificity, lower dosage, increase duration of activity, decrease side effects, and reduce risk of developing tolerance and/or addiction. Combinations of adrenergic and opioid drugs are someti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Robert Root-Bernstein
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2022-02-01
Sarja:Pharmaceuticals
Aiheet:
Linkit:https://www.mdpi.com/1424-8247/15/2/214
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