Efficacy of subanaesthetic esketamine on the prevention of postoperative delirium in older adult patients after cardiovascular surgery: protocol for a single-centre, randomised, double-blind, placebo-controlled trial (SEPDOC trial) in China

Introduction Postoperative delirium (POD) is a common and serious complication in older adult patients undergoing cardiovascular surgery. Esketamine is known for its anti-inflammatory and neuroprotective properties. While it has shown preventive effects on POD in those not undergoing cardiovascular...

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Principais autores:	Wei Zhang, Liang Zhao, Ju-Min Yan, Qing-Ren Liu, Jian-Jun Yang, Hong-Qi Lin, Zhao-Yu Wen, Hao-Ran Zhang, Yi-Xin Mei, Rui-Di Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 2025-06-01
coleção:	BMJ Open
Acesso em linha:	https://bmjopen.bmj.com/content/15/6/e089719.full
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