Major bioactive metabolites derived from Tripterygium wilfordii: structures, mechanisms, and therapeutic potentials

Tripterygium wilfordii, a traditional Chinese botanical drug, has emerged as a rich source of bioactive metabolites with promising therapeutic potential. Among its metabolites, diterpenoids and triterpenoids—such as triptolide, triptonide, and celastrol—exhibit potent immunosuppressive, anti-inflamm...

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Principais autores:	Yujie Jin, Jiahao Xu, Xiangyu Yan, Ruoting Tong, Zhanyan Zhang, Ye Ling, Yan Ma, Chenglin Huang, Qixia Zhan, Xiaojian Leng, Junjun He, Lizhuo Wang, Jialin Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-07-01
Colecção:	Frontiers in Pharmacology
Assuntos:	celastrol diterpenoids pharmacological mechanisms toxicity Tripterygium wilfordii triptolide
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1664766/full
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