VAR2CSA-specific IgG and IgM antibodies are markers of exposure and protection against adverse malaria pregnancy outcomes

Abstract Background Placental malaria is caused by the binding of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) protein VAR2CSA, found on the surface of infected erythrocytes, to placental tissue. Complications include maternal anaemia, low birth weight, small for gestational age...

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Autores principales:	Akachukwu M. Onwuka, Elizabeth H. Aitken, Wina Hasang, Mwayiwawo Madanitsa, Victor Mwapasa, Kamija Phiri, Feiko O. ter Kuile, Stephen J. Rogerson
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-12-01
Colección:	Malaria Journal
Materias:	Placental malaria VAR2CSA Low birth weight Small for gestational age Preterm delivery Maternal anaemia
Acceso en línea:	https://doi.org/10.1186/s12936-025-05773-0
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