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Development of Injectable Fucoidan and Biological Macromolecules Hybrid Hydrogels for Intra-Articular Delivery of Platelet-Rich Plasma

Platelet-rich plasma (PRP) is rich in growth factors and has commonly been utilized in the repair and regeneration of damaged articular cartilage. However, the major drawbacks of direct PRP injection are unstable biological fixation and fast or burst release of growth factors. Fucoidan is a heparino...

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Main Authors: Hsien-Tsung Lu, Wan-Ting Chang, Min-Lang Tsai, Chien-Ho Chen, Wei-Yu Chen, Fwu-Long Mi
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-04-01
Series:Marine Drugs
Subjects:
fucoidan
genipin
hydrogels
drug delivery
growth factors
platelet-rich plasma
Online Access:https://www.mdpi.com/1660-3397/17/4/236
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