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Reissner fibre-induced urotensin signalling from cerebrospinal fluid-contacting neurons prevents scoliosis of the vertebrate spine

Reissner fibre (RF), discovered by the 19th-century German anatomist Ernst Reissner, is a filamentous structure present in cerebrospinal fluid (CSF). RF forms by aggregation of a glycoprotein called SCO-spondin (Sspo), but its function has remained enigmatic. Recent studies have shown that zebrafish...

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Principais autores: Hao Lu, Aidana Shagirova, Julian L. Goggi, Hui Li Yeo, Sudipto Roy
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2020-05-01
Serier:Biology Open
Fag:
cilia
cerebrospinal fluid
reissner fibre
cerebrospinal fluid-contacting neurons
urotensin-related peptide
slow-twitch muscle
Online adgang:http://bio.biologists.org/content/9/5/bio052027
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