Immunohistochemical expression of NRF2 is correlated with the magnitude of inflammation and fibrosis in chronic liver disease

Abstract Background The nuclear factor E2‐related factor 2–Kelch‐like Ech‐associated protein (NRF2–KEAP1) pathway is a major cellular defense mechanism against oxidative stress. However, the role of NRF2–KEAP1 signaling in the development of chronic liver disease remains unclear. Methods Clinical li...

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Библиографические подробности

Главные авторы:	Keii To, Kosuke Okada, Takahisa Watahiki, Hideo Suzuki, Kiichiro Tsuchiya, Katsutoshi Tokushige, Masakazu Yamamoto, Shun‐ichi Ariizumi, Junichi Shoda
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2023-10-01
Серии:	Cancer Medicine
Предметы:	chronic liver disease hepatocellular carcinoma KEAP1 NASH NRF2
Online-ссылка:	https://doi.org/10.1002/cam4.6538
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