From mechanotransduction to manual therapy: advances in piezo/TRP channels and lumbar degeneration

Degenerative lumbar spondylolisthesis and related lumbar instability involve more than segmental biomechanical imbalance. They also involve disturbed mechanotransduction mediated by mechanosensitive ion channels. This review brings together basic, mechanobiological, and clinical studies on Piezo1, P...

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Principais autores:	Zhennan Liu, Tianzhong Peng, Wenli Li, Manhua Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-07-01
Series:	Frontiers in Physiology
Assuntos:	lumbar degenerative disease manual therapy mechanotransduction piezo ion channels review TRP channels
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1853712/full
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