YBX1 orchestrates LDHA-mediated metabolic reprogramming and NF-κB activation to drive clear cell renal cell carcinoma progression

Abstract Renal cell carcinoma (RCC) is sometimes referred to as a “metabolic disease”, as nearly all types of RCC are associated with the reprogramming of glucose and lipid metabolism. Y-box binding protein 1 (YBX1) plays a crucial regulatory role in the development and progression of various cancer...

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Hauptverfasser:	Yihan Dong, Aixin Qiu, Shuang Liu, Yuejing Pan, Tianyu Lin, Rui Wang, Ruibing Chen, Huamao Jiang, Yang Yu, Yong Wang, Dan Yue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2026-01-01
Schriftenreihe:	Cell Death and Disease
Online-Zugang:	https://doi.org/10.1038/s41419-025-08261-0
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