Dramatic Consequences of Reducing Erythrocyte Membrane Cholesterol on Plasmodium falciparum

ABSTRACT Cholesterol is the most abundant lipid in the erythrocyte. During its blood-stage development, the malaria parasite establishes an active cholesterol gradient across the various membrane systems within the infected erythrocyte. Interestingly, some antimalarial compounds have recently been s...

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Bibliographic Details

Main Authors:	Avantika I. Ahiya, Suyash Bhatnagar, Joanne M. Morrisey, Josh R. Beck, Akhil B. Vaidya
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2022-02-01
Series:	Microbiology Spectrum
Subjects:	malaria Plasmodium falciparum parasite extrusion cholesterol dynamics PfATP4 and PfNCR1 inhibitors vomocytosis
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00158-22
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