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Clinical use of CCR5 inhibitors in HIV and beyond

<p>Abstract</p> <p>Since the discovery of CCR5 as a coreceptor for HIV entry, there has been interest in blockade of the receptor for treatment and prevention of HIV infection. Although several CCR5 antagonists have been evaluated in clinical trials, only maraviroc has been approved for clinical use...

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Autores principales: Gilliam Bruce, Riedel David, Redfield Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2010-01-01
Colección:Journal of Translational Medicine
Acceso en línea:http://www.translational-medicine.com/content/9/S1/S9
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