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The deubiquitinase USP7 stabilizes HER2 expression and promotes breast cancer progression

The overexpression and amplification of HER2 occurs in breast cancer. However, the mechanism of HER2 action in tumor has not yet been elucidated. HER2 can be degraded by the UPS system, and several HER2-associated E3s have been identified, but the DUB for HER2 has not yet been uncovered. Targeted th...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiaoyue He, Xiaohong Xia, Ziying Lei, Mengfan Tang, Jiangyu Zhang, Yuning Liao, Hongbiao Huang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2025-08-01
Seri Bilgileri:Neoplasia: An International Journal for Oncology Research
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S1476558625000727
Etiketler: Etiketle
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