Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?

The 5-phospho-α-D-ribose 1-diphosphate (PRPP) metabolite plays essential roles in several biosynthetic pathways, including histidine, tryptophan, nucleotides, and, in mycobacteria, cell wall precursors. PRPP is synthesized from α-D-ribose 5-phosphate (R5P) and ATP by the Mycobacterium tuberculosis p...

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Autors principals:	Ardala Breda, Leonardo K B Martinelli, Cristiano V Bizarro, Leonardo A Rosado, Caroline B Borges, Diógenes S Santos, Luiz A Basso
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2012-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC3380012?pdf=render
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