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Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury

After complete spinal cord injury, spinal segments below the lesion maintain inter-segmental communication via the intraspinal propriospinal network. Here, the authors show that neurons in these circuits can be chemogenetically modulated to improve locomotor function in mice after spinal cord injury...

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Kaydedildi:
Asıl Yazarlar: Benedikt Brommer, Miao He, Zicong Zhang, Zhiyun Yang, Jessica C. Page, Junfeng Su, Yu Zhang, Junjie Zhu, Emilia Gouy, Jing Tang, Philip Williams, Wei Dai, Qi Wang, Ryan Solinsky, Bo Chen, Zhigang He
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2021-02-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-021-20980-4
Etiketler: Etiketle
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