Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice

A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated for the delivery of antisense oligonuclotides (AOs), 2′-O-methyl phosphorothioate RNA (2′-OMePS) and phosphorodiamidate morpholino oligomer (PMO) in cell culture and dystro...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Mingxing Wang, Bo Wu, Jason D Tucker, Lauren E Bollinger, Peijuan Lu, Qilong Lu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2016-01-01
Σειρά:	Molecular Therapy: Nucleic Acids
Θέματα:	antisense delivery exon-skipping muscular dystrophy nanoparticle polyethylenimine modification
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2162253117300689
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