Heparanase 2 (Hpa2)- a new player essential for pancreatic acinar cell differentiation
Abstract Heparanase 2 (Hpa2, HPSE2) is a close homolog of heparanase. Hpa2, however, lacks intrinsic heparan sulfate (HS)-degrading activity, the hallmark of heparanase enzymatic activity. Mutations of HPSE2 were identified in patients diagnosed with urofacial syndrome (UFS), a rare genetic disorder...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2023-07-01
|
| Seri Bilgileri: | Cell Death and Disease |
| Online Erişim: | https://doi.org/10.1038/s41419-023-05990-y |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|