The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids

The activation of the δ-class carbonic anhydrase (CAs, EC 4.2.1.1) from the diatom Thalassiosira weissflogii (TweCAδ) was investigated using a panel of natural and non-natural amino acids and amines. The most effective activator of TweCAδ was d-Tyr (KA of 51 nM), whereas several other amino acids an...

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主要な著者:	Andrea Angeli, Fatmah A. S. Alasmary, Sonia Del Prete, Sameh M. Osman, Zeid AlOthman, William A. Donald, Clemente Capasso, Claudiu T. Supuran
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis Group 2018-01-01
シリーズ:	Journal of Enzyme Inhibition and Medicinal Chemistry
主題:	Carbonic anhydrase metalloenzymes diatoms activators Thalassiosira weissflogii
オンライン･アクセス:	http://dx.doi.org/10.1080/14756366.2018.1447570
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