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Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease

<h4>Background</h4> Formation of complexes between transglutaminase 2 (TG2) and gluten can mechanistically explain why TG2 serves both as B-cell autoantigen and as an enzyme that creates deamidated gluten epitopes in coeliac disease (CeD). A model has been proposed where TG2 released from shed epith...

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Bibliografiske detaljer
Principais autores: Sunniva F. Amundsen, Jorunn Stamnaes, Knut E. A. Lundin, Ludvig M. Sollid
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2023-01-01
Serier:PLoS ONE
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298751/?tool=EBI
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