TMEM251 loss-induced autophagy dysfunction in the anterior cingulate cortex contributes to chronic postoperative pain

Abstract Macroautophagy/autophagy plays a crucial role in maintaining nervous system homeostasis but its role in chronic postoperative pain (CPOP) remains poorly understood. Here, we identify impaired autophagy and the accumulation of synaptic proteins in the anterior cingulate cortex (ACC) during t...

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मुख्य लेखकों:	Yaowei Xu, Fei Xing, Xin Wei, Xiaoling Wang, Xiaoshan Shi, Zhongyu Wang, Na Xing, Jingjing Yuan, Zhisong Li, Wei Zhang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Springer Nature 2025-12-01
श्रृंखला:	EMBO Reports
विषय:	Anterior Cingulate Cortex Autophagy Chronic Postoperative Pain Synaptic Plasticity Transmembrane Protein 251
ऑनलाइन पहुंच:	https://doi.org/10.1038/s44319-025-00646-8
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