The Effects of <i>BRCA1</i> and <i>BRCA2</i> Promoter Methylation on Clinicopathological Characteristics and Clinical Outcomes in HGSOC

Ovarian cancer is a highly lethal disease. Tumors with a deficiency in the homologous recombination repair pathway (HRD) resulting from mutations in <i>BRCA1</i>/<i>2</i> genes have a favorable response to platinum-based chemotherapy and targeted therapy with PARP inhibitors (PARPi) mediated by synt...

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Hauptverfasser:	Katarina Živić, Ivana Boljević, Milica Nedeljković, Milana Matović, Radmila Janković, Miljana Tanić
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-02-01
Schriftenreihe:	Cells
Schlagworte:	high-grade serous ovarian cancer methylation-specific PCR promoter region <i>BRCA1/2</i> genes
Online-Zugang:	https://www.mdpi.com/2073-4409/15/3/277
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