Effectiveness and safety of algorithm for treating pregnant women with syphilis and history of immediate allergy to penicillin

Background: Penicillin is the only proven effective treatment for pregnant women with syphilis. Objective: We evaluated the efficacy and safety of an algorithm to guide reexposure to penicillin in pregnant women with syphilis and a history of allergy to the drug; and identified predictive biomarkers...

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Autori principali:	Bruna Gehlen, MD, André Feodrippe, MD, Juliana Fóes Bianchini Garcia, MD, PhD, Marcelo Vivolo Aun, MD, PhD, Jorge Kalil, MD, PhD, Pedro Giavina-Bianchi, MD, PhD
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-11-01
Serie:	Journal of Allergy and Clinical Immunology: Global
Soggetti:	Gestational syphilis immediate hypersensitivity reactions anaphylaxis desensitization provocation benzathine penicillin
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2772829325001730
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