Beyond the VSG layer: Exploring the role of intrinsic disorder in the invariant surface glycoproteins of African trypanosomes.

In the bloodstream of mammalian hosts, African trypanosomes face the challenge of protecting their invariant surface receptors from immune detection. This crucial role is fulfilled by a dense, glycosylated protein layer composed of variant surface glycoproteins (VSGs), which undergo antigenic variat...

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Hauptverfasser:	Hagen Sülzen, Alexander N Volkov, Rob Geens, Farnaz Zahedifard, Benoit Stijlemans, Martin Zoltner, Stefan Magez, Yann G-J Sterckx, Sebastian Zoll
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2024-04-01
Schriftenreihe:	PLoS Pathogens
Online-Zugang:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012186&type=printable
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