Design, synthesis and antitumor activity of 3,4,5-Trisubstituted Isoxazoles
In this study, 56 isoxazole derivatives were synthesized and their antitumor activity against 9 cancer cells, such as BXPC-3, MiaPaCa-2, PANC-1, MCF-7, HCT-116, HepG2, NCI-H460, A549 and B16 was detected. The results of pharmacological experiments indicated that most compounds exhibit good cytotoxic...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2024-12-01
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| Serier: | European Journal of Medicinal Chemistry Reports |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S277241742400075X |
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