Innovative Nanocarriers: Elastic Aspasomes Loaded with Metformin Hydrochloride for Effective Management of Melasma: In Vitro Studies and Clinical Appraisal

<b>Background/Objectives</b>: Aspasomes (ASPs) are composed of ascorbyl palmitate (AP), which has antioxidant activity. The objective of this study was the formulation of aspasomes (ASPs) loaded with metformin hydrochloride (MFC) for the topical treatment of melasma. <b>Methods</b>: MFC-ASPs were pr...

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Autors principals:	Rofida Albash, Abdurrahman M. Fahmy, Maha H. Ragaie, Shimaa S. Ahmed, Rabab A. El-Gazar, Amira B. Kassem, Manar Adel Abdelbari, Hoda A. Salem, Asmaa Saleh, Shaimaa Mosallam
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-03-01
Col·lecció:	Pharmaceutics
Matèries:	melasma metformin hydrochloride aspasomes clinical study topical drug delivery
Accés en línia:	https://www.mdpi.com/1999-4923/18/3/364
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