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Synergistic Inhibitory Effect of Polymyxin B in Combination with Ceftazidime against Robust Biofilm Formed by Acinetobacter baumannii with Genetic Deficiency in AbaI/AbaR Quorum Sensing

ABSTRACT Carbapenem resistance of Acinetobacter baumannii poses challenges to public health. Biofilm contributes to the persistence of A. baumannii cells. This study was designed to investigate the genetic relationships among carbapenem resistance, polymyxin resistance, multidrug resistance, biofilm...

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Principais autores: Yinyue Li, Bo Wang, Feng Lu, Juhee Ahn, Wenwen Zhang, Liangliang Cai, Jiahui Xu, Yi Yin, Qingchao Cao, Zhenyu Ren, Xinlong He
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-02-01
coleção:Microbiology Spectrum
Assuntos:
Acinetobacter baumannii
carbapenem resistance
polymyxin B
antibiofilm formation
quorum sensing
Acesso em linha:https://journals.asm.org/doi/10.1128/spectrum.01768-21
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