Development of potent HLA-A02:01-restricted peptide-based cytotoxic T-cells against SARS-CoV-2 infections in patients awaiting a kidney transplant

BackgroundControlling viral infections prior to solid organ transplantation is vital for successful engraftment and overall well-being of patients. One promising approach involves the deployment of viral antigen-specific cytotoxic T cells to eradicate viral pathogens. Although there have been attemp...

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Autori principali:	Chih-Chao Chang, Ya Nan Liu, Zheng Xu, Elena-Rodica Vasilescu, Ping Li, Eric K. Ho, Muyang Li, Syed A. Husain, Govind Bhagat, Sumit Mohan, George Vlad, Nicole Suciu-Foca
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-10-01
Serie:	Frontiers in Immunology
Soggetti:	SARS-CoV-2 COVID-19 T-cell therapy tetramer organ transplant cell-mediated immunity
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1664371/full
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