Life-Threatening Adverse Events Following Therapeutic Opioid Administration in Adults: Is Pharmacogenetic Analysis Useful?

BACKGROUND: Systemic approaches are needed to understand how variations in the genes associated with opioid pharmacokinetics and response can be used to predict patient outcome. The application of pharmacogenetic analysis to two cases of life-threatening opioid-induced respiratory depression is pres...

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Auteurs principaux:	Parvaz Madadi, Johanna Sistonen, Gregory Silverman, Rebecca Gladdy, Colin J Ross, Bruce C Carleton, Jose C Carvalho, Michael R Hayden, Gideon Koren
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2013-01-01
Collection:	Pain Research and Management
Accès en ligne:	http://dx.doi.org/10.1155/2013/518012
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