DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

Objective: To test the hypothesis that human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature in imprinting centers of H19, SNRPN, and KCNQ1OT1 during in vitro cell culture. Materials and Methods: By bisulfite genomic sequencing, we analyzed the imprinting centers of three...

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Hauptverfasser:	Hsiu-Huei Peng, Shuenn-Dyh Chang, An-Shine Chao, Chao-Nin Wang, Po-Jen Cheng, Shiaw-Min Hwang, Tzu-Hao Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2012-09-01
Schriftenreihe:	Taiwanese Journal of Obstetrics & Gynecology
Schlagworte:	amniotic fluid mesenchymal stem cell DNA methylation human imprinting gene single-cell clones
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1028455912001180
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