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ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation[S]

The objective of this study was to determine whether 5-lipoxygenase (ALOX5) gene variants associated with cardiovascular disease affect eicosanoid production by monocytes. The study was a randomized, double-masked, parallel intervention trial with fish oil (5.0 g of fish oil daily, containing 2.0 g...

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Autori principali: Charles B. Stephensen, Patrice Armstrong, John W. Newman, Theresa L. Pedersen, Jillian Legault, Gertrud U. Schuster, Darshan Kelley, Susanna Vikman, Jaana Hartiala, Rami Nassir, Michael F. Seldin, Hooman Allayee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2011-05-01
Serie:Journal of Lipid Research
Soggetti:
arachidonic acid
eicosanoids
leukotrienes
lipoxygenase
nutrition
omega-3 fatty acids
Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520408855
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