Unspecified asthma, childhood-onset, and adult-onset asthma have different causal genes: a Mendelian randomization analysis

IntroductionAsthma is a heterogeneous condition that is characterized by reversible airway obstruction. Childhood-onset asthma (COA) and adult-onset asthma (AOA) are two prominent asthma subtypes, each with unique etiological factors and prognosis, which suggests the existence of both shared and dis...

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Hlavní autoři:	Roan E. Zaied, Sreemol Gokuladhas, Caroline Walker, Justin M. O’Sullivan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-11-01
Edice:	Frontiers in Immunology
Témata:	Mendelian randomization childhood-onset asthma adult-onset asthma gene regulatory networks SNP function genetic risk
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1412032/full
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