HIF1A-dependent overexpression of MTFP1 promotes lung squamous cell carcinoma development by activating the glycolysis pathway

Introduction: Mitochondrial fission process 1 (MTFP1) is an inner mitochondrial membrane (IMM) protein implicated in the development and progression of various tumors, particularly lung squamous cell carcinoma (LUSC). This study aims to provide a more theoretical basis for the treatment of LUSC. Met...

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Hauptverfasser:	Jing Ji, Yasong Wang, Aixin Jing, Ling Ma, Jiayan Yang, Dexu Ren, Jinyu Lv, Mingxiao Lv, Menghan Xu, Qing Yuan, Xinhui Ma, Qilan Qian, Weiling Wang, Ting Geng, Yuanyuan Ding, Jingting Qin, Yuanyuan Liu, Jiaojiao Zhou, Lingyi Zuo, Shaojie Ma, Xiujun Wang, Bin Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-04-01
Schriftenreihe:	Heliyon
Schlagworte:	Lung squamous cell carcinoma MTFP1 HIF1A Glycolysis Proliferation Migration
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405844024044712
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