Recapitulating Trafficking of Nucleosides Into the Active Site of Polymerases of RNA Viruses: The Challenge and the Prize

Nucleoside analogs are very effective antiviral agents with currently over 25 compounds approved for the therapy of viral infections. Still, their successful use against RNA viruses is very recent, despite RNA viruses comprising some of the most damaging human pathogens (e.g., Coronaviruses, Influen...

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Hlavní autoři:	Yves Boulard, Stéphane Bressanelli
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-12-01
Edice:	Frontiers in Medical Technology
Témata:	RNA virus polymerase inhibitor nucleoside analog drugs hepatitis C virus (HCV) SARS-CoV-2
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmedt.2021.705875/full
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